Elypta granted US patent for its liquid biopsy method based on cancer metabolism

Elypta granted US patent for its liquid biopsy method based on cancer metabolism
Jan 28, 2021

The molecular diagnostics firm Elypta announced today that it has been granted a patent by the United States Patent and Trademark Office for its novel liquid biopsy method for cancer diagnostics.

The patent (USPTO 10895576) concerns a method for screening for renal cell carcinoma, the most common form of kidney cancer, by measuring specific metabolites – glycosaminoglycans (GAGs) – non-invasively, through for example blood or urine samples.

Elypta was founded in 2017 following an initial discovery in Jens Nielsen lab, Chalmers University of Technology in Sweden. Here, a systems biology research approach identified GAG biosynthesis as the most deregulated metabolic pathway in renal cell carcinoma.

“This is a pivotal moment for Elypta. This patent recognizes the core invention at the basis of our liquid biopsy platform for early cancer detection. It has been a long journey since we first observed a correlation between GAGs and renal cell carcinoma,” says Francesco Gatto, co-inventor and co-founder of Elypta.

In 2019 Elypta launched the pivotal study AURORAX-087A (co-funded by the European Union’s Horizon 2020 research and innovation programme under grant agreement No 849251). The study aims to validate this method for the early detection of renal cell carcinoma recurrence after surgery. Elypta intends to use the findings to seek FDA clearance for its liquid biopsy . AURORAX-0087A. is the largest ever prospective multi-center study in renal cell carcinoma diagnostics. The study is slated to conclude in 2023.

About Elypta

Elypta is a Swedish molecular diagnostics company focused on reducing cancer mortality by enabling earlier detection and closer monitoring. The metabolism-based liquid biopsy platform in development measures a novel panel of biomarkers and utilizes machine learning algorithms to generate cancer-type specific GAG scores. Elypta is advancing a broad study program across different cancers with the first indication expected to be early detection of recurrence in renal cell carcinoma.

For further information, please contact:

Karl Bergman, CEO, Tel: +46 73 262 53 33

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